Author (Year)	Groups Studied and Intervention	Results and Findings	Conclusions
Perry et al. (2017)[@65082]	Overview of 15 reviews of alternative therapies for fibromyalgia using AMSTAR and ROBIS to evaluate quality.	Low-quality evidence supporting acupuncture improvements in pain compared to standard or no treatment. "Good" evidence supporting no difference between real vs. sham.	Limited effectiveness of real acupuncture for fibromyalgia. High-quality RCTs are needed to further assess efficacy and side effects.
Ozen et al. (2019)[@65085]	44 female patients with newly diagnosed fibromyalgia and randomized to either 10 sessions of acupuncture or 15 sessions of PT modalities (hot packs, TENS, and ultrasound to tender points)	Improvements in SF-MPQ and FIQ scores for both treatment groups. There was no difference in scores between groups.	PT modalities and acupuncture are effective in treating fibromyalgia, though one is not superior to another.
Vittorio et al. (2020)[@65086]	60 female patients were randomized to either receive Migratens® or acupuncture for three months.	Acupuncture reduced pain at one-, two-, and three-month intervals post-initiation of therapy. Migratens® improved pain at one month with improvement at three-month.	Migratens® and acupuncture seem effective options in the treatment of fibromyalgia.
Bai et al. (2014)[@65088]	Meta-analysis of 9 trials which included comparing a) real vs. sham acupuncture, b) acupuncture vs. drugs, and c) acupuncture + drugs + exercise vs. drugs + exercise.	a) Statistically significant difference in VAS, FIQ, and multidisciplinary pain inventory in real vs. sham acupuncture 4 weeks posttreatment, but not 7 weeks posttreatment. b) Statistically significant difference in VAS and tender point count after acupuncture + moxibustion when compared to either amitriptyline or fluoxetine at 4 weeks posttreatment c) Statistically significant difference in pressure pain threshold with acupuncture + drugs + exercise when compared to exercise + drugs alone at three- and six-month intervals. This did not extend to 12 and 24 months.	Insufficient evidence to support the superiority of real acupuncture over sham in fibromyalgia treatment. Evidence supporting acupuncture effectiveness over pharmacologic treatments, though the evidence was considered low quality or high-risk bias. Acupuncture combined with drugs and exercise could increase pain thresholds, but further study is needed.
Chen et al. (2019)[@65089]	Review of RCTs of acupuncture vs. control or vs. pharmacologic therapy in treating chronic pain.	Three trials reported improved pain outcomes in fibromyalgia after acupuncture when compared to nonpenetrating needles at acupoints and remained at one- and three-month follow-up. Five trials reported improved pain outcomes in fibromyalgia patients after acupuncture therapy when compared to eight weeks of fluoxetine.	Evidence supporting acupuncture over no treatment in chronic pain management with reasonable evidence supporting acupuncture superiority over drugs. Effectiveness was rated low-quality due to inadequate study.